Cyclin



Cyclin (CYC) activate CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, CYCA are active in the S phase, CYCD regulate the transition from G1 to S.

CYCA2
3my5, 2wpa, 2wxv, 2wih, 2wip, 3f5x, 3eoc, 3eid, 3ej1, 3dog, 3ddp, 3ddq, 3bht, 2v22, 2uue, 2i40, 2bkz, 2c5n, 2c5o, 2c5v, 2c5x, 2c5y, 2bpm, 2c4g, 1fvv – hCYCA2 +CDK2+inhibitor - human

3bhu, 3bhv, 2uzd, 2uzb, 2uze, 2uzl, 2uzn, 2uzo, 2iw6, 2iw8, 2iw9, 2g9x, 1oi9, 1oiu, 1oiy, 1ogu, 1p5e, 1pkd, 1h1p, 1h1q, 1h1r, 1h1s - hCYCA2 +CDK2 T160P+inhibitor

1fin - hCYCA2 +CDK2

1vyw - hCYCA2 C-terminal + hCDK2

1jst - hCYCA2 +CDK2 T160P

1vin – CYCA3 - bovine

1e9h – hCYCA3 +CDK2 T160P+inhibitor

1h24, 1h25, 1h26, 1h27, 1h28, 1gy3 - hCYCA2 +CDK2 T160P+peptide

2cjm - hCYCA2 +CDK2 T160P Y15P

2cch - hCYCA2 +CDK2 T160P+ATP analog

2cci - hCYCA2 +CDK2 T160P+CDC homolog

2wma, 2wmb, 2x1n, 2wev, 2wfy, 2whb, 1okv, 1okw, 1ol1, 1ol2, 1urc, 1qmz - hCYCA2 +CDK2+peptide

CYCB1
2b9r – hCYCB1 (mutant)

2jgz - hCYCB1 +CDK2

CYCD
2w96, 2w99, 2w9f, 2w9z - hCYCD1 +CDK4 (mutant)

3g33 – hCYCD3 +CDK4

CYCE
1w98 – hCYCE1 +CDK2 T160P

CYCH
1kxu, 1jkw – hCYCH

CYCK
2i53 – hCYCK N-terminal

CYCT
3blh - hCYCT1 +CDK9

3blq - hCYCT1 +CDK9+ATP

3lq5 – hCYCT1 (mutant)+CDK9

3blr - hCYCT1 +CDK9+inhibitor

3my1 - hCYCT1 (mutant)+CDK9+inhibitor

3mi9, 3mia - hCYCT1 +CDK9+protein TAT

2pk2 - hCYCT1/protein TAT

2w2h - CYCT1 +protein TAT + RNA – horse

2ivx – hCYCT2 (mutant)

CYC
2pk9 – yCYC PHO80 +CDK PHO85 – yeast

2pmi - yCYC PHO80 +CDK PHO85+ATPgS

Viral CYC
2euf, 2f2c, 2xo2, 1jow – V-CYC viral+hCDK6 – Herpesvirus

1bu2 – V-CYC

1xo2 - V-CYC + hCDK6 + inhibitor

1g3n - V-CYC viral+hCDK6+CDK6 inhibitor

1f5q - V-CYC g viral+hCDK2